Synthesis and evaluation of the application potential of ferritin-encapsulated metal nanoparticles
CIC nanoGUNE Seminars
- Speaker
-
Lianbing Zhang, Nanomaterials Group
- When
-
2012/03/05
12:00 - Place
- nanoGUNE seminar room, Tolosa Hiribidea 76, Donostia - San Sebastian
- Add to calendar
- iCal
Catalytic activities form one of major properties of nanoparticles. Some of
these activities resemble biological enzymes that fulfill and support the
intact biological processes. Pt and PtAu nanoparticles are synthesized with
apoferritin as the template. The hybrid composites exhibit catalytic
activities of H2O2 decomposition and superoxide-dismutation. These activities
are similar with the biological enzymes, catalase and superoxide dismutase
(SOD), respectively. In vitro tests in Caco-2 cells demonstrated that these
synthesized hybrid materials can functions as catalase and SOD to help the
cells to conquer the oxidative stress. As a natural cellular component,
apoferritin makes the composite highly biocompatible and enables a tunable
cellular uptake of nanoparticles.