Self-Assembly of Virus Nanoparticles for Materials Applications

CIC nanoGUNE Seminars

Qian Wang,Department of Chemistry and Biochemistry University of South Carolina, USA
nanoGUNE seminar room, Tolosa Hiribidea 76, Donostia - San Sebastian
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Self-Assembly of Virus Nanoparticles for Materials Applications Our group works on using functional proteins and protein nanoparticles (like viruses) as building blocks for materials development and biomedical applications. The protein based nanoparticles can be readily obtained in large quantity and modified with chemical and genetic methods. In particular, compared with the synthetic macromolecules, the uniform shape and size of viral particles provide highly promising possibilities in self-assembly study for the construction of nanoscale materials with hierarchical ordering. On the basis of the surface modification with conventional bioconjugation chemistry, “click” reaction, and genetic modification, we can control the self- assembly of spherical particles and rod-like viruses with polymers to form 1D, 2D and 3D self-assemblies. These hierarchically assembled biomaterials offer a unique scaffold for vaccine delivery and tissue engineering applications. ** Host** : A. Bittner