Self-Assembly of Virus Nanoparticles for Materials Applications
CIC nanoGUNE Seminars
- Speaker
-
Qian Wang,Department of Chemistry and Biochemistry University of South Carolina, USA
- When
-
2016/06/08
13:00 - Place
- nanoGUNE seminar room, Tolosa Hiribidea 76, Donostia - San Sebastian
- Add to calendar
- iCal
Our group works on using functional proteins and protein nanoparticles (like
viruses) as building blocks for materials development and biomedical
applications. The protein based nanoparticles can be readily obtained in large
quantity and modified with chemical and genetic methods. In particular,
compared with the synthetic macromolecules, the uniform shape and size of
viral particles provide highly promising possibilities in self-assembly study
for the construction of nanoscale materials with hierarchical ordering. On the
basis of the surface modification with conventional bioconjugation chemistry,
“click†reaction, and genetic modification, we can control the self-
assembly of spherical particles and rod-like viruses with polymers to form 1D,
2D and 3D self-assemblies. These hierarchically assembled biomaterials offer a
unique scaffold for vaccine delivery and tissue engineering applications.
**
Host** : A. Bittner