Pillar[5]arene scaffolds for the preparation of advanced materials and bioactive compounds

DIPC Seminars

Speaker

Jean-François Nierengarten
CNRS and University of Strasbourg

When

2024/07/22
12:00

Place

Faculty of Chemistry, Salón de Actos

Host

Jon Mattin Matxain Beraza

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One important aspect of modern chemistry is directed towards the synthesis of complex nano-molecules that exhibit specific properties for applications in materials science and biology. However, the preparation of complex nanostructures combining the required functional groups remains often difficult and requires a large number of synthetic steps thus limiting both their accessibility and applicability. Our research group has shown that the preparation of easily accessible nanoscaffolds allowing for the grafting of one or more molecular entities is an appealing strategy to generate sophisticated nanomolecules. Overall, one of our main concerns is to increase the complexity of the molecular structures without increasing the synthetic difficulties. This is an important challenge for synthetic organic chemistry in general. As part of this research, we became interested in pillar[5]arene1 as compact scaffolds for the construction of nanomaterials. Our latest advances in this particular field will be presented.

References
[1] For selected examples, see: (a) T. M. N. Trinh, I. Nierengarten, H. Ben Aziza, E. Meichsner, M. Holler, M. Chessé, R. Abidi, C. Bijani, Y. Koppel, E. Maisonhaute, B. Delavaux-Nicot, J.-F. Nierengarten, Chem. Eur. J. 2017, 23, 11011-11021. (b) M. Steffenhagen, A. Latus, T. M. N. Trinh,
I. Nierengarten, I. T. Lucas, S. Joiret, J. Landoulsi, B. Delavaux-Nicot, J.-F. Nierengarten, E. Maisonhaute, Chem. Eur. J. 2018, 24, 1701. (c) O. Bettucci, J. Pascual, S.-H. Turren-Cruz, A. Cabrera-Espinoza, W. Matsuda, S. F. Völker, H. Köbler, I. Nierengarten, G. Reginato, S. Collavini,
S. Seki, J.-F. Nierengarten, A. Abate, J. L. Delgado, Chem. Eur. J. 2021, 27, 8110. (d) M. Rémy, I. Nierengarten, B. Park, M. Holler, U. Hahn, J.-F. Nierengarten, Chem. Eur. J. 2021, 27, 8492. (e) N. Becharguia, E. Wasielewski, R. Abidi, I. Nierengarten, J.-F. Nierengarten, Chem. Eur. J. 2024, 30, e202303501. (f) N. Becharguia, I. Nierengarten, J.-M. Strub, S. Cianférani, M. Rémy, E. Wasielewski, R. Abidi, J.-F. Nierengarten, Chem. Eur. J. 2024, 30, e202304131.