Synthesis, design and development of molecular and colloidal materials with photoinduced and plasmonic properties


This experimental research line focuses on the synthesis, functionalization and characterization of different types of nanostructures and the study of their photochemical and plasmonic properties. An important part of the research activity is based on the study of the photochemical activation of molecules with potential therapeutic interest, as well as on the synthesis of nanoparticles that can develop biomimetic functions.

Specific topics

  • Bioorthogonal catalytic photoactivation of bioactive molecules.
  • Novel nanomaterials for chemical and optical conversion.
  • Dynamics of hot carrier relaxation in photo-excited plasmonic nanoparticles.
  • Plasmon-driven photoreduction.

Related publications

  1. Scientific article 1 Metal substrate catalysis in the confined space for platinum drug delivery
    S. Velasco-Lozano, S. Alonso-de Castro, C. Sanchez-Cano, I. Benitez-Mateos, F. Lopez-Gallego, and L. Salassa
    Chem. Sci. 13, 59 (2022).
  2. Scientific article 2 Size- and Ligand-Dependent Transport of Nanoparticles in Matricariachamomilla as Demonstrated by Mass Spectroscopy and X-ray FluorescenceImaging
    Y. Liu, C. Kornig, B. Qi, O. Schmutzler, T. Staufer, C. Sanchez-Cano, E. Magel, J. C. White, N. Feliu, F. Gruner, and W. J. Parak
    ACS Nano 16, 12941 (2022).
  3. Scientific article 3 Single-Cell Chemistry of Photoactivatable Platinum Anticancer Complexes
    E. M. Bolitho, C. Sanchez-Cano, H. Shi, P. D. Quinn, M. Harkiolaki, C. Imberti, and P. J. Sadler
    J. Am. Chem. Soc. 143, 20224 (2021).
  4. Scientific article 4 I-124 Radiolabeling of a Au-III-NHC Complex for In Vivo BiodistributionStudies
    F. Guarra, A. Terenzi, C. Pirker, R. Passannante, D. Baier, E. Zangrando, V. Gomez-Vallejo, T. Biver, C. Gabbiani, W. Berger, J. Llop, and L. Salassa
    Angew. Chem.-Int. Edit. 59, 17130 (2020).
  5. Scientific article 5 Flavin Bioorthogonal Photocatalysis Toward Platinum Substrates
    J. Gurruchaga-Pereda, V. Martinez-Martinez, E. Rezabal, X. Lopez, C. Garino, F. Mancin, A. L. Cortajarena, and L. Salassa
    ACS Catal. 10, 187 (2020).
  6. Scientific article 6 Bioorthogonal Catalytic Activation of Platinum and Ruthenium Anticancer Complexes by FAD and Flavoproteins
    S. Alonso-de Castro, A. L. Cortajarena, F. Lopez-Gallego, and L. Salassa
    Angew. Chem.-Int. Edit. 57, 3143 (2018).
  7. Scientific article 7 Riboflavin as a bioorthogonal photocatalyst for the activation of aPt-IV prodrug
    S. Alonso-de Castro, E. Ruggiero, A. Ruiz-de-Angulo, E. Rezabal, J. C. Mareque-Rivas, X. Lopez, F. Lopez-Gallego, and L. Salassa
    Chem. Sci. 8, 4619 (2017).